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Types and selection principles of liquid chromatography column packing
If the role of the chromatographic column in liquid chromatography analysis is like the human “brain”, then the chromatography packing is like our human “heart”. The quality and accuracy of liquid phase analysis have a very important relationship with fillers. There a...Read more -
How to choose a liquid chromatography column?
It can be said that the chromatographic column is the most important part of the chromatographic analysis process, equivalent to the “heart” of the human body. To choose the right liquid chromatography column according to the sample you want to analyze, you need to consider the ...Read more -
Why does the liquid chromatograph “leak” and “leak”? UHPLCS teaches you these solutions!
The liquid chromatography system is a closed system. From the very beginning solvent bottle to the last waste bottle, it is kept completely closed during the period. The mobile phase should flow in the system without leakage or external gas entering the system. An air leak has occurred. Howe...Read more -
How to solve the bubble problem in liquid chromatography analysis?
Chromatographers know that when a liquid chromatograph or high-performance liquid chromatograph is working, no bubbles can enter the system, otherwise problems such as peaks, unstable pressure fluctuations, and baseline noise will occur. Usually, it is necessary to deal with the problem of a...Read more -
Have you learned the secrets of using liquid chromatography?
Liquid chromatograph is a commonly used laboratory instrument, but even experienced “veteran drivers” can easily overlook some small details. Don’t underestimate these overlooked details, which may affect your chromatographic equipment or analysis results. ! Some glitches a...Read more -
Do you know the development of Liquid Chromatogram?
Liquid chromatographic columns are the core of liquid chromatographic analysis, and fillers have always been a hot project in the chromatographic field.The research of liquid chromatographic column can be described as the Central Plains competition, and the competition is very fierce. What ...Read more -
Hydrophobic interaction chromatography (HIC)
Hydrophobic interaction chromatography (HIC) is a must for nucleic acid separations. When combined with the advantages of monolithic chromatography, HIC meets this need while also providing an excellent solution for the purification of large biomolecules including adenoassociated viruses (AAV). H...Read more -
How to avoid the tailing problem of basic compounds in HPLC analysis?
For the Pharmaceutical workers, Alkaloids it is no a unfamiliar thing that is one of the most important and valuable biologically active ingredients in Chinese herbal medicine. Alkaloids can be divided to 59 species. They have complex structure that cannot separation well by tradition method. Bef...Read more -
What is HILIC?
Hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC is a variant of normal phase liquid chromatography that partly overlaps with other chromatographic applications such as ion chromatography and reversed phase liquid chromatography. Hydrophilic interact...Read more -
The change of HPLC stationary phase
Chromatographers alls know the important role of the selection of stationary phase.Different types of chromatograms use different stationary phases.Normal phase chromatography uses polar stationary phases (such as polyethylene glycol, amino and nitrile bonded phases), reversed phase chromatograph...Read more -
Compared with common analyticl HPLC, what is the advantage of UPLC?
The liquid chromatographic analysis most expected by chromatographic users: the highest resolution, the highest achievable sensitivity, and the fastest analysis speed. It can be said that being fast and good is the goal pursued by every industry. For this goal, the Ultra High Performance Liquid C...Read more -
Let’s learn about the Chinese Pharmacopoeia(2020 ver.)
The pharmaceutical industry has always been a key application area of high-performance liquid chromatography. High-performance liquid chromatography is widely used in drug analysis tests such as identification, impurity inspection, content determination, in vivo analysis, and the establishment of...Read more -
How to deproteinization the biological samples before HPLC analysis?
UPLCS suggests that chromatographic operators pay attention to the importance of sample filtration before performing liquid chromatographic analysis. It is mainly to prevent impurities such as proteins from being deposited on the chromatographic column, and the biological samples need to be pretr...Read more -
Exhibition review | UHPLCS is invited to attend CISILE2021
CISILE2021 was held in China National Convention Center on May 10-12.The products on display at CISILE2021 cover a variety of new products and technologies in the fields of analysis and testing instruments, measuring instruments, optical instruments and equipment, electronic optical instruments, ...Read more -
Do you know how to deal with the common fault of the UHPLC operating?
At frist, we need to know what is UHPLC, Ultra-High Performance Liquid Chromatography, is a new category and new technology in chromatographic separation science.It has been optimized in terms of manufacturing technology, diffusion volume and withstand pressure. The solid phase of small particles...Read more -
What is the stationary phase of Liquid chromatography?
In short, stationary phase is the phase that doesn’t move. The choice of stationary phase plays an important role in the separation of samples, sometimes even a decisive role. Different types of chromatography use different stationary phases, for example, the stationary phase of gas-solid c...Read more -
The contribution of liquid chromatography for food label
As the saying goes, bread is the staff of life, this shows how important it is for us the food! With the fast are pace of modern life, more and more younger have no time to cook. Thus promoted the rapid development of the fast food market.According to institutional data, the total turnover of the...Read more -
UHPLCS∣Two days activity
“Flowers flying across the day, grass see spring heart.”It is great weather to outing. To enrich the cultural life of employees and strengthen the cohesion of the company team, we held the two days activity. It was a breezy April morning. We staffed out at 8.00 am. In the CS field operations, we ...Read more -
What is a good way to select mobile phase in chromatography?
Mobile phase composition plays a crucial role in most separations.In most cases, mobile phase is mixed of water and organic solvents.In isocratic operation the composition is pre- decided and remains unchanged during the analytical run. On the other hand in gradient elution the final solvent comp...Read more -
Similarities between High Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC)
In the last new, we discussed “What Are The Differences Between Gas Chromatography (GC) And High Performance Liquid Chromatography (HPLC)?”(Click here to see it ). Today, we are talk about the common fuction between HPLC and GC, in-depth study of the commonality between them. 1.Common bas...Read more
